Thrive:
Combined HRT/Weight Loss Package
The Power Duo: Hormone Replacement Therapy and GLP-1 Medication
Weight gain, fatigue, and metabolic slowdown can be frustrating for many adults—especially during midlife transitions. If you’ve been trying to lose weight but feel like your body is working against you, you’re not alone. At Flow Wellness, we’re helping patients take a comprehensive, science-based approach to weight loss by combining two powerful therapies: Hormone Replacement Therapy (HRT) and GLP-1 medications like semaglutide or tirzepatide.
Together, these therapies don’t just support weight loss—they support total body health, energy, and hormone balance.
Why Hormones and Metabolism Matter
As we age, hormone levels—including estrogen, progesterone, testosterone, and thyroid hormones—gradually decline. These hormonal shifts can cause:
- Slower metabolism
- Increased abdominal fat
- Insulin resistance
- Fatigue and poor sleep
- Mood changes
- Muscle loss
- Increased fracture and cardiovascular risk
At the same time, metabolic health becomes more difficult to maintain. That’s where GLP-1 medications come in.

What Are GLP-1 Medications?
GLP-1 receptor agonists like semaglutide (Wegovy®) and tirzepatide (Zepbound®) mimic a naturally occurring hormone that helps regulate blood sugar, reduce appetite, and slow stomach emptying.
Benefits of GLP-1s include:
- Significant and sustained weight loss
- Reduced appetite and fewer cravings
- Lower inflammation and reduced cardiovascular risk
What Is Hormone Replacement Therapy (HRT)?
HRT involves replacing low or imbalanced hormones using bioidentical formulations of estrogen, progesterone, testosterone, or thyroid hormones. At Flow Wellness, we use customized BHRT (bioidentical hormone replacement therapy) plans to safely and effectively support hormone health.
Benefits of HRT include:
- Improved energy and sleep
- Reduction in belly fat and weight gain
- Enhanced mood and cognitive clarity
- Better libido and overall vitality
- Increased lean muscle and bone strength
Why the Combination Works So Well
GLP-1 medications and HRT address different—but interconnected—factors that affect weight, metabolism, and well-being. Together, they support long-term success by tackling the root causes of stubborn weight gain.
Here’s how they work together:
HRT
Balances estrogen, testosterone, and thyroid hormones for improved metabolism and energy
GLP-1
Who Is This Combination Right For?
This approach is especially beneficial for:
Women going through perimenopause or menopause


Personalized Wellness at Flow Wellness
At Flow Wellness, our medical team creates personalized plans based on lab testing, medical history, and your unique goals. We don’t believe in one-size-fits-all. We offer:
- Direct access to your provider
- Transparent pricing—no hidden fees
- Multiple medication options
- Monthly check-ins to monitor labs, hormones, and progress
- IV/injection therapy to optimize energy, metabolic support, and fat remodeling
Ready to Feel Like Yourself Again?
Combining hormone replacement therapy and GLP-1 medications is more than a weight loss plan—it’s a path toward vibrant health, hormonal balance, and sustained energy. Whether you’re just beginning your journey or looking to optimize the results you’ve already started, Flow Wellness is here to help you every step of the way.
You deserve a plan that works with your body—not against it.
Schedule a free 15 minute informational phone call with Dr Shena Vander Ploeg
GLP-1 medication may only be obtained with a prescription from a licensed health care provider. If your prescriber determines GLP-1 medication is right for you, obtaining a prescription is hassle-free through Flow Wellness. IV vitamin and injection therapy is not FDA approved and not intended to treat any medical condition.