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Hydration and GLP-1s: Why One Liter a Day is the Bare Minimum

Apr 3, 2025

If you’re using a GLP-1 medication you’ve likely been told to focus on smaller meals, more protein, and consistent movement. But one of the most essential—and often overlooked—parts of supporting your body on these medications is proper hydration.

Especially if you live in a dry, high-desert climate like Bend, Oregon, drinking enough water isn’t optional—it’s essential.

Why GLP-1s Make Hydration More Important

GLP-1 receptor agonists work by slowing digestion and reducing appetite. These effects help with weight loss and metabolic health, but they can also cause side effects like nausea, bloating, or constipation—particularly during the first few weeks of treatment.

Not drinking enough water can make these side effects worse. In fact, dehydration is one of the most common reasons people feel fatigued or nauseous on GLP-1s. Staying well-hydrated helps regulate digestion, reduces headaches, supports energy levels, and may even reduce cravings.

How Much Water Should You Be Drinking?

At a minimum, aim for at least one liter of water per day. But for most people, a better rule of thumb is: Half your body weight in ounces per day. (For example, someone weighing 160 lbs should drink about 80 oz—or roughly 2.4 liters—daily!!)

And if you’re living in a dry, elevated area like Bend? You may need even more. Dry air pulls moisture from your skin and respiratory system, and you often lose water without realizing it. Add in caffeine, alcohol, or increased activity, and your hydration needs climb even higher.

Signs You’re Not Drinking Enough on a GLP-1

Dehydration can look like:

  • Headaches or brain fog

  • Nausea or dizziness

  • Constipation or irregular bowel movements

  • Fatigue or low energy

  • Dry skin or lips

  • Muscle cramps

  • Lightheaded with standing up

5 Simple Tips to Stay Hydrated

  1. Start your morning with a full glass of water before anything else.

  2. Keep a water bottle with you.

  3. Add flavor with lemon, cucumber, or a water enhancer.

  4. Sip steadily throughout the day.

Should You Add Electrolytes?

For many people, the answer is yes. Rapid weight loss and reduced food intake can shift your fluid and mineral balance. Adding a well-formulated electrolyte supplement (with sodium, potassium, and magnesium) can help you stay hydrated and support energy, mood, and muscle function—especially in active or dry environments.

Hydration Is a Key Part of Success on GLP-1s

Staying hydrated may seem like a small task, but it plays a big role in helping you feel your best while on a GLP-1. It improves medication tolerance, protects your digestion, and supports overall metabolic health.

If you live in a place like Bend, Oregon, where the air is dry year-round, staying well-hydrated isn’t just helpful—it’s critical to making this journey smoother and more sustainable.

At Flow Wellness, we’re here to support every step of your path to wellness—water included.

Having Trouble Staying Hydrated? Need a Boost Fast?

If you’re finding it hard to drink enough water—and dealing with headaches, nausea, or low energy on your GLP-1—IV hydration therapy can help you bounce back fast. At our Central Oregon Flow Wellness clinic, our hydration IVs deliver fluids, electrolytes, and essential nutrients directly into your bloodstream for immediate, noticeable relief.

Whether you’re catching up after a few dry days or looking to feel your best while adjusting to your medication, we’re here to help you rehydrate, recharge, and restore your vitality.

New Patient Signature IV Special:
Your first IV is just $95 — that’s 50% off the regular price of $189!
Feel the difference—fast.  

Schedule your IV Infusion same-day or ahead of time here:  IV Infusions in Bend and Central Oregon 

At Flow Wellness, we support your journey with GLP-1 therapy and can help you optimize hydration and nutrient balance. Reach out to us for expert guidance!

Disclaimer: This blog post is for informational purposes only and should not be considered medical advice. Always consult with a healthcare provider for personalized medical advice. GLP-1 medication requires a prescription by a licensed health care provider. IV vitamin therapy is not approved by the FDA and not intended to treat any medical condition.

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Clinic locations in Bend, Oregon (Old Mill) & Seattle, Washington (South Lake Union). Telehealth in California, Oregon, & Washington

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Our medical weight loss programs are designed to deliver safe, sustainable results. We combine prescription medications, nutritional guidance, lifestyle coaching, and ongoing medical monitoring to help you lose weight, improve metabolic health, and maintain your results long-term.

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We offer hormone optimization for men and women to address fatigue, mood changes, weight gain, and other symptoms of hormonal imbalance. Our bioidentical hormone replacement programs are personalized to restore optimal levels and support overall vitality.

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Peptides are short chains of amino acids that play a vital role in cellular function and repair. At Flow Wellness, we offer personalized peptide protocols to support athletic performance, muscle recovery, and cognitive performance. Prescription supplements available for enhanced energy, hair & skin rejuvenation, and sexual health. All treatments are medically supervised for safety and results.

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Flow Wellness provides IV & oral ketamine treatments in a safe, controlled, and supportive environment. This innovative treatment has shown promise for individuals struggling with depression, anxiety, PTSD, and other mental health challenges—especially when traditional therapies have been ineffective. IV treatments available at our Bend, Oregon clinic.

IV Therapy in Bend, Oregon

Our customized IV infusions deliver rapid hydration and essential nutrients directly into your bloodstream for maximum absorption. Whether you’re looking to boost your immune system, recover from illness, enhance athletic performance, or simply feel more energized, our IV therapy options are designed to meet your specific needs.

Why patients love working with us:

  • Transparent pricing and no guesswork
  • Auto-pay and referral discounts
  • Fast shipping or in-clinic pickup
  • Friendly, experienced medical providers who really care

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