Is My GLP-1 Still Good If the Ice Pack Is Melted?
If you’ve ever opened your delivery of compounded GLP-1 medication and found the ice pack melted, you’re not the only one. Patients worry about this all the time—and the good news is:
YES, your medicine is still good!
Why GLP-1 Shipments Include Ice Packs
Pharmacies and compounding pharmacies ship GLP-1 medications with ice packs to help maintain a cooler environment during transit. But here’s the key: the ice pack is not supposed to stay frozen the whole way. In fact, it’s completely normal for it to be melted when your package arrives.
How Stable Are GLP-1 Medications in Transit?
Both FDA-approved GLP-1 medications (Ozempic®, Wegovy®, Mounjaro®, Zepbound™) and compounded versions are formulated to remain stable at room temperature for several days. Shipping methods are designed with this in mind.
That means:
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Melted ice pack ≠ spoiled medication
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Your GLP-1 is still effective if it arrived within the expected shipping window
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Whether from a retail pharmacy or a compounding pharmacy, it’s safe to use once refrigerated
Storage Guidelines Once You Receive It
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Refrigerator (preferred): Store between 36°F and 46°F (2°C–8°C)
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Room temperature (backup): Most GLP-1s are stable at room temp for up to 28 days (check the instructions on your specific prescription or compounded product)
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Avoid extremes: Do not freeze. Do not leave in a hot car or direct sunlight.
When to Call the Pharmacy
Melted ice packs are expected, but reach out to your pharmacy or clinician if:
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Your package was significantly delayed
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The box was damaged or exposed to extreme heat
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The medication looks unusual (cloudy, discolored, or leaking)
Bottom Line
It makes sense to worry when you see a melted ice pack—most people do. But the truth is, your GLP-1 is designed to handle the trip. As long as it arrived on time and looks normal, it’s safe to use. Pop it in the fridge, take your next dose with confidence, and know you’re doing the right thing to care for your health.
