How To Take Oral Ketamine

by | Dec 7, 2023

How do I take an oral dissolving tablet (ODT)?

The stomach breaks down ketamine, so if it is swallowed it will not be as effective.  The ODT tablets should be placed under the tongue (you can use a mirror) and kept there for 15 minutes. Set a timer.  Avoid talking, eating, or drinking during the 15 minutes.  The tablet may taste bitter.  Often saliva will build up in the mouth.  This is normal.  Try to minimize swallowing unless necessary.  You may not feel anything unusual during the first 15 minutes. Start to prepare your mind and body for the experience.  

What should I expect?

After 15 minutes swallow the saliva or spit in your mouth.  Find your relaxing space and focus on your breathing and your intention.  You will likely slowly drift into a deeper space.  It is best to surrender to the experience rather than fight it.  You will likely find yourself letting go of the experience and see where it is taking you.  If the experience is distressing, focus on your breathing.  One deep slow inhale and then one deep long exhale.  Repeat.  Remember that the experience will change and will end.  As the experience fades out, try and stay in your internal space as long as you can.  As you come back to reality, expect to feel relaxed.  Your balance will be off and you may feel disoriented and/or groggy.  Move very slowly.  A light snack and a glass of water can be helpful.  Plan a relaxing day afterwards.

Your timing may vary but this timeline is common for most patients:

0-15 minutes: Tablet dissolving in mouth, minimal effects

15-45 minutes: Full effect of dose

45-75 minutes: Dose gradually wears off, awakening to regular consciousness

75 mins – 120 mins: Side effects of balance issues and grogginess resolve

10-12 hrs: Ketamine out of system, ok to drive and go back to work

We require a trusted person to be nearby (immediately available by voice) in case you need any assistance.  Contact us if you would like to do your treatment in our clinic. You should not drive or operate machinery the entire day after a session. Also, avoid making any major decisions that could have personal or financial consequences during treatment. Be careful getting up after the treatment and use caution on stairs. Use your trusted person to help with moving if you feel off balance. These effects will usually go away within an hour or two after the intense experience.

This blog post is intended for educational purposes only and should not be considered a substitute for professional medical advice.

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